Presence/absence of taxa
Tool | Gold standard | CLARK_v1.1.3 | CommonKmers | FOCUS | MetaPhlAn2.0 db_v20 | MetaPhyler_V1.25 | mOTU_1.1.1 | Quickr | Taxy-Pro | Taxy-Pro_sjanssen | TIPP_1.1 |
---|---|---|---|---|---|---|---|---|---|---|---|
Completeness (recall)Completeness (recall): ratio of taxa correctly predicted as present and all taxa present at the selected taxonomic rank. It ranges from 0 (worst) to 1 (best). |
1 ( 0standard error: 0 ) |
1 ( 0standard error: 0 ) |
1 ( 0standard error: 0 ) |
1 ( 0standard error: 0 ) |
1 ( 0standard error: 0 ) |
1 ( 0standard error: 0 ) |
1 ( 0standard error: 0 ) |
1 ( 0standard error: 0 ) |
1 ( 0standard error: 0 ) |
1 ( 0standard error: 0 ) |
1 ( 0standard error: 0 ) |
Purity (precision)Purity (precision): ratio of taxa correctly predicted as present and all predicted taxa at the selected taxonomic rank. It ranges from 0 (worst) to 1 (best). |
1 ( 0standard error: 0 ) |
0.633 ( 0.0333standard error: 0.0333 ) |
0.867 ( 0.0816standard error: 0.0816 ) |
1 ( 0standard error: 0 ) |
1 ( 0standard error: 0 ) |
1 ( 0standard error: 0 ) |
1 ( 0standard error: 0 ) |
0.667 ( 0standard error: 0 ) |
0.733 ( 0.0667standard error: 0.0667 ) |
0.933 ( 0.0667standard error: 0.0667 ) |
1 ( 0standard error: 0 ) |
F1 scoreF1 score: harmonic average of completeness and purity at the selected taxonomic rank. It ranges from 0 (worst) to 1 (best). |
1 ( 0standard error: 0 ) |
0.773 ( 0.0267standard error: 0.0267 ) |
0.92 ( 0.049standard error: 0.049 ) |
1 ( 0standard error: 0 ) |
1 ( 0standard error: 0 ) |
1 ( 0standard error: 0 ) |
1 ( 0standard error: 0 ) |
0.8 ( 0standard error: 0 ) |
0.84 ( 0.04standard error: 0.04 ) |
0.96 ( 0.04standard error: 0.04 ) |
1 ( 0standard error: 0 ) |
True positivesTrue positives: number of taxa correctly predicted as present at the selected taxonomic rank. |
2 ( 0standard error: 0 ) |
2 ( 0standard error: 0 ) |
2 ( 0standard error: 0 ) |
2 ( 0standard error: 0 ) |
2 ( 0standard error: 0 ) |
2 ( 0standard error: 0 ) |
2 ( 0standard error: 0 ) |
2 ( 0standard error: 0 ) |
2 ( 0standard error: 0 ) |
2 ( 0standard error: 0 ) |
2 ( 0standard error: 0 ) |
False positivesFalse positives: number of taxa incorrectly predicted as present at the selected taxonomic rank. |
0 ( 0standard error: 0 ) |
1.2 ( 0.2standard error: 0.2 ) |
0.4 ( 0.245standard error: 0.245 ) |
0 ( 0standard error: 0 ) |
0 ( 0standard error: 0 ) |
0 ( 0standard error: 0 ) |
0 ( 0standard error: 0 ) |
1 ( 0standard error: 0 ) |
0.8 ( 0.2standard error: 0.2 ) |
0.2 ( 0.2standard error: 0.2 ) |
0 ( 0standard error: 0 ) |
False negativesFalse negatives: number of taxa incorrectly predicted as absent at the selected taxonomic rank. |
0 ( 0standard error: 0 ) |
0 ( 0standard error: 0 ) |
0 ( 0standard error: 0 ) |
0 ( 0standard error: 0 ) |
0 ( 0standard error: 0 ) |
0 ( 0standard error: 0 ) |
0 ( 0standard error: 0 ) |
0 ( 0standard error: 0 ) |
0 ( 0standard error: 0 ) |
0 ( 0standard error: 0 ) |
0 ( 0standard error: 0 ) |
Jaccard indexJaccard index: indicator of similarity between the sets of true and predicted taxa at the seletec taxonomic rank computed as the ratio of the number of taxa in the intersection of these sets to the number of taxa in their union. It ranges from 0 (complete dissimilarity) to 1 (complete overlap). |
1 ( 0standard error: 0 ) |
0.633 ( 0.0333standard error: 0.0333 ) |
0.867 ( 0.0816standard error: 0.0816 ) |
1 ( 0standard error: 0 ) |
1 ( 0standard error: 0 ) |
1 ( 0standard error: 0 ) |
1 ( 0standard error: 0 ) |
0.667 ( 0standard error: 0 ) |
0.733 ( 0.0667standard error: 0.0667 ) |
0.933 ( 0.0667standard error: 0.0667 ) |
1 ( 0standard error: 0 ) |
Abundance estimates
Tool | Gold standard | CLARK_v1.1.3 | CommonKmers | FOCUS | MetaPhlAn2.0 db_v20 | MetaPhyler_V1.25 | mOTU_1.1.1 | Quickr | Taxy-Pro | Taxy-Pro_sjanssen | TIPP_1.1 |
---|---|---|---|---|---|---|---|---|---|---|---|
Weighted UniFrac errorWeighted UniFrac error: tree-based measure of similarity between the true and predicted abundances at all taxonomic ranks ranging from 0 (high similarity) to 16 (low similarity). |
0 ( 0standard error: 0 ) |
5.45 ( 0.0565standard error: 0.0565 ) |
7.65 ( 0.0569standard error: 0.0569 ) |
7.14 ( 0.0485standard error: 0.0485 ) |
9.37 ( 0.0752standard error: 0.0752 ) |
6.39 ( 0.0214standard error: 0.0214 ) |
8.67 ( 0.0431standard error: 0.0431 ) |
7.79 ( 0.0526standard error: 0.0526 ) |
5.31 ( 0.0151standard error: 0.0151 ) |
7.47 ( 0.016standard error: 0.016 ) |
6.96 ( 0.0372standard error: 0.0372 ) |
Unweighted UniFrac errorUnweighted UniFrac error: similar to the weighted UniFrac error, but measuring how well a profiler correctly identified the presence and absence of taxa instead of their relative abundances. The maximal value is the product of the number of taxonomic ranks minus 1 and the number of true taxa at all taxonomic ranks. |
0 ( 0standard error: 0 ) |
8.5e+03 ( 39.3standard error: 39.3 ) |
5.58e+03 ( 100standard error: 100 ) |
5.39e+03 ( 38.9standard error: 38.9 ) |
6.27e+03 ( 39.4standard error: 39.4 ) |
1.18e+04 ( 68.4standard error: 68.4 ) |
6.31e+03 ( 81.4standard error: 81.4 ) |
9.93e+03 ( 123standard error: 123 ) |
5.59e+03 ( 25.8standard error: 25.8 ) |
1.13e+04 ( 160standard error: 160 ) |
7.16e+03 ( 57.1standard error: 57.1 ) |
L1 norm errorL1 norm error: sum of the absolute differences between the true and predicted abundances at the selected taxonomic rank ranging from 0 (perfect reconstruction of the relative abundances) to 2 (totally incorrect reconstruction). |
0 ( 0standard error: 0 ) |
0.0159 ( 0.00195standard error: 0.00195 ) |
0.0241 ( 0.00431standard error: 0.00431 ) |
0.0279 ( 0.00339standard error: 0.00339 ) |
0.14 ( 0.0203standard error: 0.0203 ) |
0.000988 ( 7.47e-05standard error: 7.47e-05 ) |
0.258 ( 0.0373standard error: 0.0373 ) |
0.0721 ( 0.00264standard error: 0.00264 ) |
0.00888 ( 0.00118standard error: 0.00118 ) |
0.00879 ( 0.00121standard error: 0.00121 ) |
0.00772 ( 0.00105standard error: 0.00105 ) |
Bray-Curtis distanceBray-Curtis distance: normalized form of the L1 norm ranging from 0 to 1. |
0 ( 0standard error: 0 ) |
0.00796 ( 0.000973standard error: 0.000973 ) |
0.0121 ( 0.00216standard error: 0.00216 ) |
0.014 ( 0.0017standard error: 0.0017 ) |
0.0701 ( 0.0102standard error: 0.0102 ) |
0.000494 ( 3.73e-05standard error: 3.73e-05 ) |
0.129 ( 0.0186standard error: 0.0186 ) |
0.036 ( 0.00132standard error: 0.00132 ) |
0.00444 ( 0.000591standard error: 0.000591 ) |
0.0044 ( 0.000604standard error: 0.000604 ) |
0.00386 ( 0.000526standard error: 0.000526 ) |
Alpha diversity
Tool | Gold standard | CLARK_v1.1.3 | CommonKmers | FOCUS | MetaPhlAn2.0 db_v20 | MetaPhyler_V1.25 | mOTU_1.1.1 | Quickr | Taxy-Pro | Taxy-Pro_sjanssen | TIPP_1.1 |
---|---|---|---|---|---|---|---|---|---|---|---|
Taxon countsTaxon counts: number of predicted taxa at the selected taxonomic rank. |
2 ( 0standard error: 0 ) |
3.2 ( 0.2standard error: 0.2 ) |
2.4 ( 0.245standard error: 0.245 ) |
2 ( 0standard error: 0 ) |
2 ( 0standard error: 0 ) |
2 ( 0standard error: 0 ) |
2 ( 0standard error: 0 ) |
3 ( 0standard error: 0 ) |
2.8 ( 0.2standard error: 0.2 ) |
2.2 ( 0.2standard error: 0.2 ) |
2 ( 0standard error: 0 ) |
Shannon diversityShannon diversity: ranges from 0 to the natural logarithm of the number of predicted taxa, where the latter represents maximal possible diversity with all taxa being evenly represented. |
0.0635 ( 0.00643standard error: 0.00643 ) |
0.0966 ( 0.00948standard error: 0.00948 ) |
0.114 ( 0.0149standard error: 0.0149 ) |
0.119 ( 0.0017standard error: 0.0017 ) |
0.28 ( 0.0291standard error: 0.0291 ) |
0.063 ( 0.00648standard error: 0.00648 ) |
0.399 ( 0.0379standard error: 0.0379 ) |
0.224 ( 0.00482standard error: 0.00482 ) |
0.043 ( 0.00422standard error: 0.00422 ) |
0.0432 ( 0.00414standard error: 0.00414 ) |
0.0799 ( 0.00773standard error: 0.00773 ) |
Shannon equitabilityShannon equitability: normalized form of Shannon diversity index ranging from 0 to 1 with 1 indicating complete evenness. |
0.0916 ( 0.00928standard error: 0.00928 ) |
0.0851 ( 0.0104standard error: 0.0104 ) |
0.134 ( 0.0128standard error: 0.0128 ) |
0.172 ( 0.00245standard error: 0.00245 ) |
0.403 ( 0.0419standard error: 0.0419 ) |
0.0909 ( 0.00934standard error: 0.00934 ) |
0.576 ( 0.0546standard error: 0.0546 ) |
0.203 ( 0.00439standard error: 0.00439 ) |
0.0444 ( 0.00771standard error: 0.00771 ) |
0.0566 ( 0.00517standard error: 0.00517 ) |
0.115 ( 0.0112standard error: 0.0112 ) |